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benzodiazepine officially indicated for management of seizure disorders and panic disorder. The use of a drug for its approved indications is called its
labeled use. In clinical practice, however, physicians often prescribe medications for unlabeled (“off-label”) uses when published clinical studies, case
reports, or their own clinical experiences support the efficacy and safety of those treatments. Physicians may use Klonopin outside its approved
indications to treat social anxiety disorder, posttraumatic stress disorder, agitation in acute psychosis and mania, and premenstrual syndrome. As with
other benzodiazepines, Klonopin is associated with dependence and abuse and is regulated as a controlled substance by state and federal laws.
Klonopin’s effectiveness for treating anxiety may be explained by its pharmacological action in the brain at specific receptor sites. Receptors are
specific sites on the nerve cell membrane that receive a signal from a neurochemical called the neurotransmitter. Once a neurotransmitter locks in on the receptor, the neurochemical signal is changed to an electrical or another chemical signal and travels down the neuron. The receptor sites in which benzodiazepines elicit their action are found in various regions of the brain, and the specific receptors are also known as benzodiazepine receptors. The coupled reaction of benzodiazepines to the receptors facilitates the inhibitory action of the neurotransmitter γ-aminobutyric acid (GABA) in that region of the brain. Benzodiazepines’ action on GABA receptors appears to produce their anxiolytic, sedative, and anticonvulsant actions. Klonopin, for example, is an effective anxiolytic, hypnotic, and antiseizure medication.
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Take this medication by mouth as directed by your doctor, usually 2 or 3 times daily.
Buy Klonopin Online Legally and take your dosage based on your medical condition, age, and response to treatment. For children, the dose is also based on weight. Older adults usually start with a lower dose to decrease the risk of side effects. Do not increase your dose, take it more often, or take it for a longer time than directed.
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Take this medication regularly to get the most benefit from it. To help you remember, take it at the same times each day.
Do not stop taking this medication without consulting your doctor. Some conditions may become worse when this drug is suddenly stopped. Your dose may need to be gradually decreased.
COMMON SIDE EFFECTS
The most common side effects reported with Klonopin are sedation and drowsiness, especially shortly after initiating therapy. Other frequent symptoms are impaired concentration and memory, feeling of dissociation (“spacey”), and impaired coordination.
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Klonopin should not be used in patients with a history of sensitivity to benzodiazepines, nor in patients with clinical or biochemical evidence of significant liver disease. It may be used in patients with open angle glaucoma who are receiving appropriate therapy but is contraindicated in acute narrow angle glaucoma.
Interference With Cognitive and Motor Performance: Since Klonopin produces CNS depression, patients receiving this drug should be cautioned against engaging in hazardous occupations requiring mental alertness, such as operating machinery or driving a motor vehicle. They should also be warned about the concomitant use of alcohol or other CNS-depressant drugs during Klonop.